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Multiple Choice

During crossmatching, if a strong reaction is observed and there is uncertainty about patient identity, what is the recommended action?

When a strong reaction occurs during crossmatching and patient identity is uncertain, patient safety demands stopping the crossmatch and verifying identity before proceeding. A vigorous reaction can signal incompatibility or a clerical/sample mix-up, and transfusing to the wrong patient would be dangerous. Begin by confirming the patient’s identity with at least two identifiers (for example, wristband and chart), and ensure the specimen label matches the patient. If identity is confirmed, repeat the crossmatch with the correctly identified specimen and the appropriate donor units. If the reaction persists or identity cannot be established, do not transfuse and escalate for further investigation and supervisor involvement. Document all steps taken.

When a strong reaction occurs during crossmatching and patient identity is uncertain, patient safety demands stopping the crossmatch and verifying identity before proceeding. A vigorous reaction can signal incompatibility or a clerical/sample mix-up, and transfusing to the wrong patient would be dangerous. Begin by confirming the patient’s identity with at least two identifiers (for example, wristband and chart), and ensure the specimen label matches the patient. If identity is confirmed, repeat the crossmatch with the correctly identified specimen and the appropriate donor units. If the reaction persists or identity cannot be established, do not transfuse and escalate for further investigation and supervisor involvement. Document all steps taken.