Identify the blood group from this serology: Anti-A 0, Anti-B 4+, Anti-D 4+, RhC 0, A1 Cells 4+, B cells 0, Dolichos biflorus 0?

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Multiple Choice

Identify the blood group from this serology: Anti-A 0, Anti-B 4+, Anti-D 4+, RhC 0, A1 Cells 4+, B cells 0, Dolichos biflorus 0?

Understanding ABO and Rh serology patterns helps you pick the correct blood group from a panel like this. Forward typing looks for which antigens are on the patient’s red cells (reactivity with anti-A and anti-B), while reverse typing looks for which antibodies are in the patient’s plasma (reactivity of the plasma with A1 cells and B cells). Rh typing checks for the D antigen (and sometimes others like C) on the red cells. In this pattern, there is no reaction with anti-A, but there is a strong reaction with anti-B. That means the patient’s red cells do not have A antigen but do have B antigen. So the ABO type is B. The reverse typing shows strong agglutination of A1 cells by the patient’s serum (A1 cells 4+), and no agglutination of B cells (B cells 0). This indicates the serum contains anti-A antibodies but not anti-B antibodies, which is exactly what you expect if the person is blood type B. Rh typing shows a strong reaction with anti-D (RhD positive), so the person is Rh positive. The RhC result being negative just adds a detail about the C antigen status, but it doesn’t change the ABO/Rh positive conclusion. The Dolichos biflorus result helps distinguish A1 from other A subtypes; a lack of reactivity here supports that the cells are not A1, aligning with the B type interpretation. Putting it together: B positive is the blood group that fits all the results.

Understanding ABO and Rh serology patterns helps you pick the correct blood group from a panel like this. Forward typing looks for which antigens are on the patient’s red cells (reactivity with anti-A and anti-B), while reverse typing looks for which antibodies are in the patient’s plasma (reactivity of the plasma with A1 cells and B cells). Rh typing checks for the D antigen (and sometimes others like C) on the red cells.

In this pattern, there is no reaction with anti-A, but there is a strong reaction with anti-B. That means the patient’s red cells do not have A antigen but do have B antigen. So the ABO type is B. The reverse typing shows strong agglutination of A1 cells by the patient’s serum (A1 cells 4+), and no agglutination of B cells (B cells 0). This indicates the serum contains anti-A antibodies but not anti-B antibodies, which is exactly what you expect if the person is blood type B.

Rh typing shows a strong reaction with anti-D (RhD positive), so the person is Rh positive. The RhC result being negative just adds a detail about the C antigen status, but it doesn’t change the ABO/Rh positive conclusion.

The Dolichos biflorus result helps distinguish A1 from other A subtypes; a lack of reactivity here supports that the cells are not A1, aligning with the B type interpretation.

Putting it together: B positive is the blood group that fits all the results.

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