If RhC is negative, which antigen is absent from the red cells?

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Multiple Choice

If RhC is negative, which antigen is absent from the red cells?

The RhC status tells you about the C antigen on the red cell surface. The Rh system includes D and the C/c and E/e antigen pairs; the term RhC specifically refers to the C antigen on the RhCE glycoprotein. If RhC is negative, the C antigen is not present on the red cells, while D and other Rh antigens can be present or absent independently. So the absent antigen is C. In practice, a RhC negative individual would require C-negative red cells to avoid alloimmunization.

The RhC status tells you about the C antigen on the red cell surface. The Rh system includes D and the C/c and E/e antigen pairs; the term RhC specifically refers to the C antigen on the RhCE glycoprotein. If RhC is negative, the C antigen is not present on the red cells, while D and other Rh antigens can be present or absent independently. So the absent antigen is C. In practice, a RhC negative individual would require C-negative red cells to avoid alloimmunization.

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