In ABO backward typing, what is the purpose of A1 Cells and B Cells?

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Multiple Choice

In ABO backward typing, what is the purpose of A1 Cells and B Cells?

Backward typing looks for antibodies in the patient’s serum against A and B antigens. A1 cells and B cells act as reagent red cells carrying the A and B antigens, respectively. When you test the patient’s serum with A1 cells, anti-A antibodies (if present) cause agglutination of those cells; testing with B cells detects anti-B antibodies. This setup reveals which antibodies are circulating, helping to determine the ABO type. They are not used to express antigens (that's forward typing) and they don’t remove antibodies.

Backward typing looks for antibodies in the patient’s serum against A and B antigens. A1 cells and B cells act as reagent red cells carrying the A and B antigens, respectively. When you test the patient’s serum with A1 cells, anti-A antibodies (if present) cause agglutination of those cells; testing with B cells detects anti-B antibodies. This setup reveals which antibodies are circulating, helping to determine the ABO type. They are not used to express antigens (that's forward typing) and they don’t remove antibodies.

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