Interpret the saliva inhibition test results: Saliva + Anti-A + A cells: +; Saliva + Anti-B + B cells: 0; Saliva + Anti-H + H cells: 0. What is the most likely secretor group?

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Multiple Choice

Interpret the saliva inhibition test results: Saliva + Anti-A + A cells: +; Saliva + Anti-B + B cells: 0; Saliva + Anti-H + H cells: 0. What is the most likely secretor group?

The test uses soluble ABH antigens in saliva to see if they inhibit the action of specific antisera on their corresponding red cells. If saliva contains the antigen, it will soak up (inhibit) the antibody, so the antibody can’t agglutinate the target cells. - With anti-A and A cells, agglutination occurs. This means A antigen is not present in the saliva, so anti-A remains active and can clump A cells. - With anti-B and B cells, no agglutination is observed. This indicates B antigen is present in the saliva, inhibiting anti-B. - With anti-H and H cells, no agglutination is observed. This shows H antigen is present in the saliva, inhibiting anti-H. Putting it together: saliva contains B antigen and H antigen but not A antigen. That pattern corresponds to a Group B secretor (they secrete B and H in saliva).

The test uses soluble ABH antigens in saliva to see if they inhibit the action of specific antisera on their corresponding red cells. If saliva contains the antigen, it will soak up (inhibit) the antibody, so the antibody can’t agglutinate the target cells.

  • With anti-A and A cells, agglutination occurs. This means A antigen is not present in the saliva, so anti-A remains active and can clump A cells.

  • With anti-B and B cells, no agglutination is observed. This indicates B antigen is present in the saliva, inhibiting anti-B.

  • With anti-H and H cells, no agglutination is observed. This shows H antigen is present in the saliva, inhibiting anti-H.

Putting it together: saliva contains B antigen and H antigen but not A antigen. That pattern corresponds to a Group B secretor (they secrete B and H in saliva).

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