Rh immune globulin is administered to which patients?

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Multiple Choice

Rh immune globulin is administered to which patients?

Rh immune globulin prevents sensitization to the RhD antigen in an Rh-negative mother when fetal Rh-positive cells enter her circulation. If sensitized, the mother can develop anti-D antibodies that cross the placenta in later pregnancies and cause hemolytic disease in the fetus or newborn. Giving RhIG provides passive anti-D antibodies that bind any Rh-positive fetal red cells in the mother, preventing her immune system from forming its own anti-D antibodies. Therefore, the vaccine is given to Rh-negative pregnant women, and it is used after events that could cause fetomaternal hemorrhage and after delivery of an Rh-positive infant. This timing helps prevent the development of anti-D antibodies for any future pregnancies.

Rh immune globulin prevents sensitization to the RhD antigen in an Rh-negative mother when fetal Rh-positive cells enter her circulation. If sensitized, the mother can develop anti-D antibodies that cross the placenta in later pregnancies and cause hemolytic disease in the fetus or newborn. Giving RhIG provides passive anti-D antibodies that bind any Rh-positive fetal red cells in the mother, preventing her immune system from forming its own anti-D antibodies.

Therefore, the vaccine is given to Rh-negative pregnant women, and it is used after events that could cause fetomaternal hemorrhage and after delivery of an Rh-positive infant. This timing helps prevent the development of anti-D antibodies for any future pregnancies.

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