What best describes a minor crossmatch, and when is it performed?

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Multiple Choice

What best describes a minor crossmatch, and when is it performed?

A minor crossmatch checks donor plasma for antibodies that could react with the recipient’s red cells. It is used when the recipient has a negative antibody screen (no detected alloantibodies) and both donor and recipient ABO groupings have been confirmed. Under these conditions, an immediate spin crossmatch can be performed to quickly verify that the donor’s plasma antibodies will not target the recipient’s red cells. This helps prevent a hemolytic reaction from donor antibodies in plasma-containing products. If there were antibodies detected in the recipient, or if the ABOs weren’t confirmed, a different crossmatch approach would be required.

A minor crossmatch checks donor plasma for antibodies that could react with the recipient’s red cells. It is used when the recipient has a negative antibody screen (no detected alloantibodies) and both donor and recipient ABO groupings have been confirmed. Under these conditions, an immediate spin crossmatch can be performed to quickly verify that the donor’s plasma antibodies will not target the recipient’s red cells. This helps prevent a hemolytic reaction from donor antibodies in plasma-containing products. If there were antibodies detected in the recipient, or if the ABOs weren’t confirmed, a different crossmatch approach would be required.

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