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Multiple Choice

What is an electronic crossmatch and when is it performed?

An electronic crossmatch is a computer‑based check that confirms ABO compatibility between patient and donor without a physical crossmatch. It’s used when the patient has a current, negative antibody screen and there is no history of clinically significant alloantibodies, and the donor unit’s ABO type is known. The system compares the patient’s latest ABO result with prior records to ensure consistency and then authorizes the release of RBC units. It focuses on ABO compatibility and does not address antibodies, so if alloantibodies are present, a serologic crossmatch is still required. It is not used in all cases, and it does not replace crossmatching for patients with antibodies or where antigen-negative units are needed.

An electronic crossmatch is a computer‑based check that confirms ABO compatibility between patient and donor without a physical crossmatch. It’s used when the patient has a current, negative antibody screen and there is no history of clinically significant alloantibodies, and the donor unit’s ABO type is known. The system compares the patient’s latest ABO result with prior records to ensure consistency and then authorizes the release of RBC units. It focuses on ABO compatibility and does not address antibodies, so if alloantibodies are present, a serologic crossmatch is still required. It is not used in all cases, and it does not replace crossmatching for patients with antibodies or where antigen-negative units are needed.