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Multiple Choice

What is the purpose of autoabsorption?

Autoabsorption works by adsorbing the patient's own autoantibodies onto their own red blood cells, effectively removing the autoantibody from the serum. With the autoantibody cleared, any underlying alloantibody can be unmasked and identified, guiding safer transfusion decisions. This technique is especially helpful when autoantibodies cause broad reactivity and obscure the presence of clinically significant alloantibodies. It does not target alloantibodies, destroy all antibodies, or replace plasma.

Autoabsorption works by adsorbing the patient's own autoantibodies onto their own red blood cells, effectively removing the autoantibody from the serum. With the autoantibody cleared, any underlying alloantibody can be unmasked and identified, guiding safer transfusion decisions. This technique is especially helpful when autoantibodies cause broad reactivity and obscure the presence of clinically significant alloantibodies. It does not target alloantibodies, destroy all antibodies, or replace plasma.