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Multiple Choice

What is the purpose of the IS phase?

The immediate spin phase targets antibodies that react at room temperature, mainly IgM antibodies responsible for ABO incompatibilities. Because ABO antibodies are typically IgM and cause rapid agglutination, this phase acts as a quick screen for ABO mismatches before proceeding to more sensitive tests. It does not detect IgG antibodies, which require the AHG/IAT phases, and it is not a test for complement. So the purpose is to detect IgM antibodies and ABO incompatibilities.

The immediate spin phase targets antibodies that react at room temperature, mainly IgM antibodies responsible for ABO incompatibilities. Because ABO antibodies are typically IgM and cause rapid agglutination, this phase acts as a quick screen for ABO mismatches before proceeding to more sensitive tests. It does not detect IgG antibodies, which require the AHG/IAT phases, and it is not a test for complement. So the purpose is to detect IgM antibodies and ABO incompatibilities.