What is the role of plasma transfusion in correcting coagulopathy?

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Multiple Choice

What is the role of plasma transfusion in correcting coagulopathy?

Plasma transfusion provides all coagulation factors, so it’s able to correct coagulopathy when multiple factors are deficient or when rapid reversal of anticoagulation is needed. Fresh frozen plasma is used to reverse anticoagulants like warfarin by supplying the vitamin K–dependent factors II, VII, IX, and X, and it’s also used in coagulopathies from liver disease, DIC, or dilutional coagulopathy during massive transfusion. This broad factor replacement helps restore hemostasis in bleeding patients when specific factor concentrates aren’t available or appropriate. It does not raise hemoglobin or replace platelets, which are the roles of red cells and platelets, respectively.

Plasma transfusion provides all coagulation factors, so it’s able to correct coagulopathy when multiple factors are deficient or when rapid reversal of anticoagulation is needed. Fresh frozen plasma is used to reverse anticoagulants like warfarin by supplying the vitamin K–dependent factors II, VII, IX, and X, and it’s also used in coagulopathies from liver disease, DIC, or dilutional coagulopathy during massive transfusion. This broad factor replacement helps restore hemostasis in bleeding patients when specific factor concentrates aren’t available or appropriate. It does not raise hemoglobin or replace platelets, which are the roles of red cells and platelets, respectively.

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