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Multiple Choice

Which of the following is not warm reacting?

Warm-reacting antibodies are IgG antibodies that bind red cells at body temperature (37°C) and are detected by the antiglobulin test; these are commonly seen with Rh, Kell, and Duffy antibodies, which react at 37°C and can cause clinically significant transfusion reactions. Lutheran antibodies, in contrast, are typically IgM and cold-reacting, meaning they react at room temperature or cooler and do not demonstrate strong reactivity at 37°C. So Lutheran antibodies are not warm reacting, while the others are.

Warm-reacting antibodies are IgG antibodies that bind red cells at body temperature (37°C) and are detected by the antiglobulin test; these are commonly seen with Rh, Kell, and Duffy antibodies, which react at 37°C and can cause clinically significant transfusion reactions. Lutheran antibodies, in contrast, are typically IgM and cold-reacting, meaning they react at room temperature or cooler and do not demonstrate strong reactivity at 37°C. So Lutheran antibodies are not warm reacting, while the others are.